Sexe royan grosse bite en boucheDunaiefs research has shown that the oral iron chelator deferiprone may be a possible treatment for AMD if iron accumulation was one of the causes for its development. Age-related macular degeneration (AMD) is regarded as the leading cause of vision loss for people over the age. Deferiprone can protect the retinas of mice by entering the retina and removing iron from it, said Dunaief, whose lab is currently testing additional drugs to prevent iron accumulation in the eye. Iron accumulates in the body with age because we continue to absorb it from our diets, but we excrete very little, Dunaief said. Joshua Dunaief, professor of ophthalmology at the University of Pennsylvania School of Medicine. The macula, a small portion of the retina which is responsible for sharp and detailed vision, deteriorates over time when the retinal pigment epithelium (RPE) surrounding the macula oxidizes triggering an inflammatory response. This means that ferritin is constantly being made no matter whether iron levels are high or low. The result is hereditary hyperferritinemia cataract syndrome (hhcs an inherited condition of early-onset cataracts which could be dangerously confused with hemochromatosis (iron overload) unless a person is diagnosed using the full iron panel : Hemoglobin : the iron-containing protein in the blood that carries iron. Right now, the only known treatment for hhcs is cataract surgery. The answer is that a genetic mutation has turned off the bodys ability to make ferritin in response to changing iron levels.
Oftentimes the storage protein for iron, ferritin, can reach the eye instead of the mineral itself. An ophthalmologist confirms site de rencontre vaud nivelles diagnosis of hhcs. Normally the RPE has ways to prevent iron from entering the retina when iron levels are high, but if iron export from cells is unregulated, iron may sexe rencontre femme annemasse webs rencontre plan cul accumulate in the eye and degrade the macula. In hhcs, components of ferritin accumulate in the eye lens and crystalize disrupting the light transmission which enables a person to see. A liver biopsy will show that the patient does not have iron overload. But how can the bodys storage sites for iron be full without iron overflowing into other organs? Iron may accumulate to even higher levels in diseased retinas because low oxygen levels (hypoxia) or inflammation can cause cells to retain iron. Attachment, posted on Mon, June 20, 2016 by site de rencontre vaud nivelles Kayla Wiles.